Review Note

Last Update: 03/02/2025 08:19 PM

Current Deck: ACG Part 2::Obstetrics

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Field Change Suggestions:
SS_OB 1.27 Evaluate methods to treat hypotension associated with neuraxial blockade for caesarean birth
Dense block to T4 leads causes sympathetic block and associated vasodilation -> leading to hypotension. 

Goal BP : within 10-20% of baseline BP unless patient has severe HTN 
  • (always <160 SBP, and <110 DBP)
  • Avoid hypotension as placental perfusion pressure dependent 


VASOPRESSORS 
  • Phenylephrine : direct alpha agonists. 25-50mcg/min 
    • Associated maternal bradycardia (more than noradrenaline) 
  • Noradrenaline low dose : 7mcg/ml, 7-14mcg bolus, 20-30mls/hr infusion
    • Less maternal bradycardia, and no significant increase in adverse affects for fetus. 
    • Increased risk of extravascular necrosis compared to phenylephrine 
  • Metaraminol 
    • Less studied than others, indirect and direct alpha agonist 
  • Ephedrine - direct and indireact alpha  + beta 
    • Associated with lower neonate pH