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Last Update: 02/18/2025 02:45 AM

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2017 a Question 21 
Impaired movement of which of the following ions is implicated in torsades de pointes? 
a) Sodium
b) Potassium
c) Chloride
d) Calcium
e) Magnesium 

a) Sodium
b) Potassium
c) Chloride
d) Calcium
e) Magnesium 
Cardiac action potential - Wikipedia
Torsades de Pointes (TdP) = type of polymorphic ventricular tachycardia (VT) that occurs in the setting of QT interval prolongation. Characterised by a twisting of the QRS complexes around the isoelectric line on an ECG.
Diagnosis of Tdp = PVT and QT prolongation
Prolonged QT interval = prolonged myocyte repolarisation due to ion channel malfunction 
Delays repolarization More time for EADs
EADs may manifest on the ECG as tall U waves; if these reach threshold amplitude they may manifest as PVCs
TdP is initiated when a PVC occurs during the preceding T wave, known as ‘R on T’ phenomenon

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