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Last Update: 01/29/2025 02:33 PM

Current Deck: PHYSIOLOGY::exam one

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What is the effect on loop with an increase in end-diastolic volume (pre-load)? What is the effect on stroke volume?
End-diastolic volume , or “preload”, is volume of blood contained in the ventricle just before contraction.  Increasing this volume means more fluid (blood) enters the ventricle during diastole and shifts the curve to the right.  Frank-Starling relationship holds that as end-diastolic volume increases, stroke volume increases (everything coming in gets pumped out).  Note the increase in the width of the pressure-volume loop