Review Note
Last Update: 11/06/2024 04:38 PM
Current Deck: BioOrganic -- Harding Section
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Commit #194638
What are the 2 general approaches to peptide synthesis?
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Commit #194638
1. Convert amino-protected amino acid to carboxyl activated form and then react this with amino function of second amino acid
2. React two amino acids together -- one of which is protected at the amino group and the other at the carboxyl group. This requires a coupling reagent to activate the carboxyl group
2. React two amino acids together -- one of which is protected at the amino group and the other at the carboxyl group. This requires a coupling reagent to activate the carboxyl group