Review Note
Last Update: 06/01/2024 08:46 PM
Current Deck: SLS Cards::5. Prenatal care
New Card (Unpublished)Currently Published Content
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Commit #104915
What is the pathophysiology of hyperemesis gravidarum?
Back
Commit #104915
Multifactorial:
- Hormonal: elevated hCG (association), estrogen (slowing gastric emptying, increase sensitivity to smells), progesterone (relax smooth muscle --> delayed gastric emptying)
- Gastroesopahgeal reflux from increased intra-abdominal pressure
- Genetic predispositions (appetite regulation and placental function)
- CNS: vomiting and chemoreceptor trigger zones increased sensitivity
- Psychological stress
- Immune
- Placental proteins: GDF15 associated
- Vitamin and mineral deficiencies