Notes in 34) Anemia of Chronic Disease

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Status	Last Update	Fields
Published	06/12/2025	What is another name for Anemia of Chronic Disease?
Published	06/12/2025	What is the most common anemia worldwide?
Published	06/12/2025	What is the second most common anemia worldwide?
Published	06/12/2025	In which conditions does ACD typically occur?
Published	06/12/2025	What is the typical RBC appearance in early ACD?
Published	06/12/2025	What RBC change occurs in long-standing ACD?
Published	06/12/2025	What kind of iron problem is ACD?
Published	06/12/2025	What defense strategy does the body use in ACD?
Published	06/12/2025	Which cytokine is most responsible for signaling hepcidin production?
Published	06/12/2025	Name two other cytokines involved in ACD pathophysiology.
Published	06/12/2025	What hormone is the master regulator of iron homeostasis?
Published	06/12/2025	What iron export channel does hepcidin bind to?
Published	06/12/2025	What happens to ferroportin when bound by hepcidin?
Published	06/12/2025	How does ACD affect dietary iron absorption?
Published	06/12/2025	How does ACD affect iron release from macrophages?
Published	06/12/2025	Where is iron primarily stored in ACD?
Published	06/12/2025	How does chronic inflammation affect erythropoietin production?
Published	06/12/2025	How does inflammation affect marrow responsiveness to EPO?
Published	06/12/2025	What additional marrow effect do cytokines have?
Published	06/12/2025	What is the 'triple whammy' in ACD?
Published	06/12/2025	How are EPO levels in ACD compared to the degree of anemia?
Published	06/12/2025	In pure CKD anemia, why is EPO low?
Published	06/12/2025	What analogy describes hepcidin's role?
Published	06/12/2025	Why don't iron pills fix ACD?
Published	06/12/2025	What is the ultimate solution to ACD?
Published	06/12/2025	Name four chronic infections causing ACD.
Published	06/12/2025	Name three autoimmune diseases causing ACD.
Published	06/12/2025	What percentage of RA patients develop anemia?
Published	06/12/2025	Name two malignancies commonly associated with ACD.
Published	06/12/2025	Why is CKD-associated anemia grouped with ACD?
Published	06/12/2025	What lab pattern is seen in CKD anemia?
Published	06/12/2025	What is the typical hemoglobin range in ACD?
Published	06/12/2025	At what Hb level in ACD should you suspect additional causes?
Published	06/12/2025	What are common symptoms of ACD?
Published	06/12/2025	What happens to serum iron in ACD?
Published	06/12/2025	What happens to TIBC in ACD?
Published	06/12/2025	What happens to transferrin in ACD?
Published	06/12/2025	What happens to ferritin in ACD?
Published	06/12/2025	How does inflammation affect transferrin?
Published	06/12/2025	How does inflammation affect ferritin?
Published	06/12/2025	What is the typical MCV in early ACD?
Published	06/12/2025	What percentage of ACD cases become microcytic?
Published	06/12/2025	What is the reticulocyte count in ACD?
Published	06/12/2025	What happens to ESR and CRP in ACD?
Published	06/12/2025	What ferritin level in inflammatory patients suggests concurrent IDA?
Published	06/12/2025	How does serum iron compare in ACD vs IDA?
Published	06/12/2025	How does TIBC compare in ACD vs IDA?
Published	06/12/2025	How does ferritin compare in ACD vs IDA?
Published	06/12/2025	How does transferrin saturation compare in ACD vs IDA?
Published	06/12/2025	How does MCV compare in ACD vs IDA?
Published	06/12/2025	How does RDW compare in ACD vs IDA?
Published	06/12/2025	How do bone marrow iron stores compare in ACD vs IDA?
Published	06/12/2025	How does ACD respond to iron therapy vs IDA?
Published	06/12/2025	Which microcytic anemia shows normal iron studies?
Published	06/12/2025	What distinguishes thalassemia minor on blood smear?
Published	06/12/2025	What is RDW like in thalassemia minor?
Published	06/12/2025	What iron pattern is seen in sideroblastic anemia?
Published	06/12/2025	What diagnostic feature is seen in sideroblastic anemia bone marrow?
Published	06/12/2025	What RBC feature is seen in lead poisoning?
Published	06/12/2025	What is the key difference in iron studies between sideroblastic anemia and ACD?
Published	06/12/2025	Why is ACD normocytic early on?
Published	06/12/2025	Why does IDA become microcytic?
Published	06/12/2025	What is anisocytosis in ACD?
Published	06/12/2025	What is the main treatment for ACD?
Published	06/12/2025	When are ESAs used in ACD?
Published	06/12/2025	What must be ensured before ESA therapy?
Published	06/12/2025	What other anemias present with low reticulocyte count and normocytic RBCs?
Published	06/12/2025	Which gene encodes hepcidin?
Published	06/12/2025	Through which signaling pathway does IL-6 upregulate hepcidin?
Published	06/12/2025	What type of reactant is transferrin?
Published	06/12/2025	What type of reactant is ferritin?
Published	06/12/2025	What does serum iron measure?
Published	06/12/2025	What does TIBC measure?
Published	06/12/2025	How is transferrin saturation calculated?
Published	06/12/2025	What does reticulocyte count reflect?
Published	06/12/2025	What does ESR measure?
Published	06/12/2025	What does CRP indicate?
Published	06/12/2025	What stain shows iron in macrophages?
Published	06/12/2025	What is functional iron deficiency?
Published	06/12/2025	Which cytokine directly induces hepcidin?
Published	06/12/2025	Name a cytokine that blunts EPO response.
Published	06/12/2025	Name a cytokine causing marrow suppression.
Published	06/12/2025	Where is hepcidin produced?
Published	06/12/2025	Why is iron sequestered in ACD?
Published	06/12/2025	What happens if iron is given in pure ACD?
Published	06/12/2025	What effect do EPO analogs have in cancer?
Published	06/12/2025	What side effect is associated with ESA use?
Published	06/12/2025	What is the RDW in ACD?
Published	06/12/2025	Why do iron pills fail in ACD?
Published	06/12/2025	Why does transferrin fall in ACD?
Published	06/12/2025	What is CRP classified as?
Published	06/12/2025	What ferritin level indicates adequate stores?
Published	06/12/2025	Primary macrophage role in iron storage?
Published	06/12/2025	Role of enterocytes in iron metabolism?
Published	06/12/2025	Unique feature of ferroportin?
Published	06/12/2025	What does ferroportin degradation cause?
Published	06/12/2025	What is the sequence in ACD pathogenesis?
Published	06/12/2025	What diagram resource explains ACD?
Published	06/12/2025	What is a UWorld question focus in ACD?
Published	06/12/2025	What is the First Aid key fact for ACD?
Published	06/12/2025	Why is pathoma explanation for ACD helpful?
Published	06/12/2025	What is the role of IL-1 in ACD?
Published	06/12/2025	What is the role of IFN-γ in ACD?
Published	06/12/2025	What is the main lab clue for ACD?
Published	06/12/2025	What clinical context suggests ACD?
Published	06/12/2025	What distinguishes ACD microcytosis from IDA?
Published	06/12/2025	How does obesity relate to ACD?
Published	06/12/2025	How does heart failure relate to ACD?
Published	06/12/2025	How does chronic lung disease relate to ACD?
Published	06/12/2025	What can ICU critical illness trigger?
Published	06/12/2025	What is the significance of Hb rarely <8 in ACD?
Published	06/12/2025	What type of anemia is ACD?
Published	06/12/2025	How is IDA classified?
Published	06/12/2025	What RBC count is seen in thalassemia trait?
Published	06/12/2025	What stains identify ringed sideroblasts?
Published	06/12/2025	When do reticulocytes increase in IDA treatment?
Published	06/12/2025	What is the target Hb with ESA in CKD?
Published	06/12/2025	What unit is TIBC measured in?
Published	06/12/2025	What unit is serum iron measured in?
Published	06/12/2025	What unit is ferritin measured in?
Published	06/12/2025	What is the normal range for TIBC?
Published	06/12/2025	Is TIBC increased or decreased in ACD?
Published	06/12/2025	Is serum iron increased or decreased in ACD?
Published	06/12/2025	Is ferritin increased or decreased in ACD?
Published	06/12/2025	What is the normal serum iron range?
Published	06/12/2025	What is the normal ferritin range?
Published	06/12/2025	What is the normal reticulocyte percentage?
Published	06/12/2025	What retic percentage indicates hypoproliferation?
Published	06/12/2025	What is the difference between ACD and anemia of renal failure?
Published	06/12/2025	Which medication can reduce ACD by blocking the IL-6 receptor?
Published	06/12/2025	What therapeutic target is under study for ACD?
Published	06/12/2025	What is the risk of indiscriminate iron supplementation in ACD?
Published	06/12/2025	Which cytokine family does IL-6 belong to?
Published	06/12/2025	Which liver signaling pathway mediates hepcidin production?
Published	06/12/2025	What cell type produces EPO?
Published	06/12/2025	What additional oxidative effect occurs in ACD?
Published	06/12/2025	How does IL-6 affect EPO levels?
Published	06/12/2025	A high-yield acronym for ACD lab pattern?
Status	Last Update	Fields